Dr. Santiago Panesso

Dr. Santiago Panesso

Obstetrics & Gynecology Resident Physician, UPMC Medical Education

MD

Dr. Santiago Panesso is a Colombian-trained physician and OB-GYN resident physician at UPMC Medical Education with research experience in ovarian cancer, women's health, pediatric infectious diseases, and parasitology in the United States and Colombia.

Current Focus Obstetrics & gynecology residency training
Languages English, Spanish
Affiliation UPMC Medical Education
Location Harrisburg, Pennsylvania
Women's Health Research Ovarian Cancer Pediatric Infectious Diseases Parasitology
Department Obstetrics & Gynecology Residency
Profiles
Profile Bilingual physician

Clinical and academic work across North and South America.

Research Research background

Published work in ovarian cancer biology, chemotherapy resistance, and women's health.

Recognition Clinical training

Medical training in Colombia followed by residency education in the United States.

About

Clinical training informed by research

Santiago Panesso is an international medical graduate from Colombia who earned his medical degree from Universidad de los Andes in 2016. His physician profile combines obstetrics and gynecology training with academic research in pediatric infectious diseases, parasitology, ovarian cancer biology, and women's health.

His professional experience includes research fellowships at Nationwide Children's Hospital in Columbus and Magee-Womens Research Institute in Pittsburgh, followed by obstetrics and gynecology residency training through UPMC Medical Education in Harrisburg, Pennsylvania.

Training

Education and training

Medical Degree

MD, Medicine

Universidad de los Andes, Bogota, Colombia, Class of 2016

Residency Training

Obstetrics & Gynecology

UPMC Medical Education, Harrisburg, Pennsylvania, 2024-2028

Employment

Clinical and research appointments

2019-Present

Magee-Womens Research Institute

Pittsburgh, Pennsylvania. Postdoctoral Research Fellow in Obstetrics and Gynecology.

2024-2028

UPMC Central Pa

Harrisburg, Pennsylvania. Resident Physician in Obstetrics and Gynecology.

2016-2017

Nationwide Children's Hospital

Columbus, Ohio. Postdoctoral Research Fellow in Pediatric Infectious Disease.

Expertise

Clinical and research focus

Clinical Experience

  • Obstetrics and gynecology residency training
  • Pediatric infectious diseases
  • Parasitology and tropical medicine
  • Women's health clinical training

Research Focus

  • Cancer cell biology
  • Chemotherapy resistance mechanisms
  • Women's health therapeutics
  • Ovarian cancer translational research

Approach

  • Translational, clinically informed investigation
  • Cross-disciplinary collaboration
  • Evidence-driven therapeutic development

Publications

Selected publications and research

2026

MRTFA/SRF Pathway and Cancer Chemoresistance

Panesso-Gómez S, Cole AJ, Arrigo A, et al. Identification of the MRTFA/SRF pathway as a critical regulator of quiescence and chemotherapy resistance in cancer. Cancer Letters. 2026.

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2024

Gastrointestinal Pathogen Testing in NEC and SIP

Talavera-Barber MM, Sánchez PJ, Conces M, Kaptsan I, Everhart K, Leber A, Malleske DT, Moallem M, Panesso-Gómez S, Shimamura M. Molecular testing for gastrointestinal pathogens in intestinal tissue of infants with necrotizing enterocolitis or spontaneous intestinal perforation. Journal of Perinatology. 2024.

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2023

Follistatin and Chemotherapy Resistance in Ovarian Cancer

Cole AJ, Panesso-Gómez S, Shah JS, Ebai T, Jiang Q, Gumusoglu-Acar E, Bello MG, Vlad A, Modugno F, Edwards RP, Buckanovich RJ. Quiescent ovarian cancer cells secrete follistatin to induce chemotherapy resistance in surrounding cells in response to chemotherapy. Clinical Cancer Research. 2023;29(10):1969-1983.

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2020

NFATC4 and Chemotherapy Resistance in Ovarian Cancer

Cole AJ, Iyengar M, Panesso-Gómez S, O'Hayer P, Chan D, Delgoffe GM, Aird KM, Yoon E, Bai S, Buckanovich RJ. NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. JCI Insight. 2020;5(7):e131486.

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2019

Cytomegalovirus in Intestinal Tissue of Infants

Panesso-Gómez S, Shimamura M, Conces M, Talavera MM, Moallem M, Sánchez PJ, Malleske DT. Detection of Cytomegalovirus in Intestinal Tissue of Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation. The Journal of Pediatrics. 2019;214:34-40.

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2018

Trypanosoma cruzi Detection in Esophageal Achalasia

Panesso-Gómez S, Pavia P, Rodríguez-Mantilla IE, Lasso P, Orozco LA, Cuellar A, Puerta CJ, Mendoza de Molano B, González JM. Trypanosoma cruzi detection in Colombian patients with a diagnosis of esophageal achalasia. The American Journal of Tropical Medicine and Hygiene. 2018;98(3):717-723.

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Contact

Contact and professional inquiries

Dr. Panesso's work spans obstetrics and gynecology, women's health research, ovarian cancer biology, and pediatric infectious diseases. For professional, clinical, or academic inquiries, use the contact details below.

Email
panessos@upmc.edu

Location
Harrisburg, PA

Program
UPMC Medical Education, Obstetrics & Gynecology Residency